Stable and compact zwitterionic polydiacetylene micelles with tumor-targeting properties.
نویسندگان
چکیده
Compact polymerized polydiacetylene-micelles with "stealth" zwitterionic surface coating were assembled and tested in a murine xenograft model of breast cancer. In vivo fluorescence imaging indicated accumulation in the tumor area and histological studies revealed predominant uptake of the micelles at the margins of the tumor, thereby allowing the delineation of its volume.
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ورودعنوان ژورنال:
- Chemical communications
دوره 51 80 شماره
صفحات -
تاریخ انتشار 2015